Monday, 11 May 2009

Cataract surgery no effect on AMD

A latest study has showed that cataract surgery has no clear effect on the worsening of Age-Related Macular Degeneration. This is contrary to earlier findings.

AMD and cataract are two of the leading causes of visual impairment in the United States. The relationship between cataract surgery and the development of advanced AMD has generated interest among ophthalmologists. Concerns have been raised regarding the potential of cataract surgery to accelerate progression to advanced, vision-threatening forms of AMD in a number of studies.

In the Age-Related Eye Disease Study Published in the Journal Opththalmology Feb 2009, the population that was followed up carefully at frequent, regular intervals for a long period showed that cataract surgery was not associated with a clinically important increase in the rates of development of advanced AMD.

However, it remains important that individuals with large drusen and pigmentary changes have an understanding of their risk for progression to advanced AMD with or without cataract surgery and that this risk is discussed with the patient before cataract surgery.

Persons with intermediate AMD (bilateral large drusen) or with unilateral advanced AMD should be aware of the fact that the risk of developing advanced AMD is as high as 50% in five years. These results are contrary to the results of some previously published epidemiologic studies, including two reports that each pooled data from different population-based studies.

The five-year results of the Beaver Dam Eye Study and the Blue Mountains Eye Study identified persons with and without a history of cataract extraction at a baseline examination and reexamined them for incident AMD at five and 10 years. They found an association between cataract surgery and the five-year incidence of late AMD.

For the Beaver Dam Eye Study, cataract surgery before baseline was associated with an increased risk of advanced AMD and in the Blue Mountains Eye Study, there was a three-fold increased risk of advanced AMD .

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